Proteomics as a tool for biomarker detection: Protein profiling in chronic and vascular disease

dr. J.A.P. Bons

Chapter 01 – Introduction

Chapter 02 – Protein profiling as a diagnostic tool in clinical chemistry, a review influence of pre- and post-analytical aspects

Chapter 03 – Standardization of calibration and quality control using surface-enhanced Laser desorption/ionization time-of-flight mass spectrometry

Chapter 04 – Clinical proteomics in chronic inflammatory diseases, a review

Chapter 05 – Potential biomarkers for diagnosis of sarcoidosis using proteomics in serum

Chapter 06 – Potential biomarkers for diagnosis of ankylosing spondylitis using SELDI-TOF-MS

Chapter 07 – Haptoglobin in lacunar stroke: a SELDI-TOF-MS study with subsequent phenotyping

Chapter 08 – A specific immunoprecipitation method for isolating isoforms of insulin-like growth factor binding protein-3 from serum

Chapter 09 – General discussion

Chapter 10 – Summary

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